Behcet’s disease (Silk Road disease): a rare inflammatory disease

Background: Behcet’s disease (Silk Road disease), a rare immune-mediated multisystem inflammatory disorder described by intermittent oralaphthae and genital ulcer, backsliding uveitis, mucocutaneous, articular, gastrointestinal, neurological vascular manifestations, with no cure.It is brought about changes in the: a) arteries that flexibly blood to the body tissues b) veins return lungs, rear of eyes retina, brain, joints, skin bowels.
 Case Presentation: A 55-year-old male patient was sensed c/o joint agony lower appendages, oral ulcer scrotal ulcer. On physical assessment cognizant oriented B/L leg emanation. All lab examination including RA factor within normal limits, diminished Serum Vitamin D. HLA B51, ANA were checked mucosal biopsy done. The most punctual sign exhibited disintegration, various shallow scarcely any dissolved knobs scrotum. At point gave pain numbness on right leg. assessment, strange motor nerve conduction saw tibial neuropathy. first, doubt syphilis tarsal tunnel following 7-8 days affirmation, analyzed as Behcet's illness dependent dermatological, rheumatologic signs. Treatment given symptomatic supportive relievers, corticosteroid, antibiotics, IV fluids, PPI, vitamin supplement, laxative local anaesthetic.
 Discussion:Without adequate data it's difficult examine, light anomaly standardized treatment are questionable at present. New information respect its immunopathogenesis, genetics will significantly help advancement research center tests, diagnostic criteria particularly decision best